Martin Eichmann Selected Research

preproinsulin

1/2018	Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes.
1/2013	Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity.
7/2012	Circulating preproinsulin signal peptide-specific CD8 T cells restricted by the susceptibility molecule HLA-A24 are expanded at onset of type 1 diabetes and kill β-cells.

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Martin Eichmann Research Topics

Disease

9	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 07/2012
2	Disease Progression 01/2020 - 01/2016
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Autoimmune Diseases (Autoimmune Disease) 11/2017
1	Neoplasms (Cancer) 12/2011

Drug/Important Bio-Agent (IBA)

4	EpitopesIBA 01/2018 - 07/2012
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2011
3	AutoantigensIBA 01/2020 - 03/2015
3	preproinsulinIBA 01/2018 - 07/2012
3	Peptides (Polypeptides)IBA 01/2017 - 01/2013
2	Protein Sorting Signals (Signal Peptide)IBA 01/2018 - 07/2012
2	Insulin (Novolin)FDA Link 01/2018 - 01/2018
2	HLA Antigens (Human Leukocyte Antigens)IBA 01/2017 - 03/2015
2	AntigensIBA 01/2016 - 03/2015
2	HLA-A24 AntigenIBA 01/2013 - 07/2012
1	SmokeIBA 01/2022
1	Abatacept (Orencia)FDA Link 01/2020
1	HLA-A Antigens (HLA-A)IBA 01/2018
1	HLA-DQ Antigens (HLA-DQ)IBA 11/2017
1	ProinsulinIBA 01/2017
1	HLA-A2 Antigen (HLA A2 Antigen)IBA 01/2013
1	ErbB Receptors (EGF Receptor)IBA 12/2011
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2011
1	Leucovorin (Folinic Acid)FDA Link 12/2011
1	Cetuximab (Erbitux)FDA Link 12/2011
1	Cadherins (E-Cadherin)IBA 12/2011
1	Monoclonal AntibodiesIBA 12/2011
1	Fluorouracil (Carac)FDA LinkGeneric 12/2011

Therapy/Procedure

4	Immunotherapy 01/2020 - 01/2016
1	Therapeutics 01/2020